GLP-1 Support Supplements

Not sure where to start? Grab a curated bundle:

The GLP-1 Companion stack covers what the bundles don't: creatine, collagen, and the B12 and magnesium that come out of the food volume you are no longer eating.

More South Africans than ever are on a GLP-1 medicine prescribed by their doctor. This collection is not about that medicine — your doctor and your pharmacist own it. It is about the nutrition alongside it.

A GLP-1 medicine changes how much you eat and how you digest it, and that creates nutritional blind spots. When a whole day's food fits on one small plate, the nutrients that come from volume — protein, B12, magnesium, fibre and the omega-3s in fatty fish — are the ones that get thin first. This shelf is about those: eating well on very little.

At One Life Health, we've curated this collection specifically for GLP-1 users — every product chosen for the nutritional needs that come up most on this journey. Start with our guide: What Supplements to Take on a GLP-1 — The South African Guide.

The Key Nutrient Depletions to Know About

Vitamin B12

Less food means less of everything in it. B12 comes largely from red meat, eggs and dairy, and those are often among the first foods to go when the appetite is much smaller. B12 contributes to normal energy-yielding metabolism and to the normal function of the nervous system. Whether yours needs looking at is a blood-test question for your doctor, not a guess made at a shelf.

Magnesium

Magnesium comes largely from greens, nuts, seeds and whole grains — volume foods, and volume is the first thing to go when you are eating much less. Magnesium contributes to normal muscle function and to normal energy-yielding metabolism. Which form to buy is the question our consultants are asked more than any other on this shelf, and the forms are genuinely not interchangeable — ask before you buy.

Muscle & Lean Mass NEW

Losing weight quickly can cost lean muscle as well as fat if protein intake and resistance training aren't protected, and less muscle means a lower metabolic rate. Creatine monohydrate (3–5g daily) is one of the most studied supplements for holding on to muscle, paired with enough protein. Our GLP-1 Companion stack is built around exactly this.

Vitamin D3 & K2

Vitamin D contributes to the maintenance of normal bones and normal muscle function, and to the normal function of the immune system. K2 contributes to the maintenance of normal bones — worth attention when weight is coming off quickly. The two are commonly taken together. Whether you are short of vitamin D is something a blood test answers and a supplement aisle does not.

Omega-3 Fatty Acids

Omega-3s are typically eaten as fatty fish — foods often reduced because of a smaller appetite or nausea. EPA and DHA contribute to the normal function of the heart, and DHA contributes to the maintenance of normal brain function and normal vision. If fish has dropped out of your week, this is the gap it leaves.

Digestive Enzymes & Probiotics

Digestion feels different for a lot of people who are eating much less than they used to. Digestive enzymes for the change in gut motility, and practitioner-range probiotics for gut and immune support, are the two things asked for most often at our counter when that happens. Anything about your digestion that worries you belongs with your doctor or pharmacist first — they can see everything you are on and we cannot.

How to Choose the Right Bundle Tier

We've built three tiers to match where you are in your journey and what level of support you're looking for. Each tier builds on the previous one.

Tier 1: GLP-1 Essentials

Tier 2: GLP-1 Complete

Tier 3: GLP-1 Premium Protocol

+ The Muscle Companion NEW

Browse the products below to build your personalised protocol, or speak to one of our consultants at any One Life Health branch in Centurion, Glen Village, or Edenvale — or WhatsApp us.