The Apothecary

Gut Health & Digestion: A Practical Apothecary Guide

Practical supplement guidance from One Life Health.

Onelife Health Gut Health and Digestion guide cover

Gut Health & Digestion: A Practical Apothecary Guide

If half the wellness internet is telling you that the gut is the second brain, the other half is selling probiotics. Most of both are wrong. The gut is genuinely important and most probiotics genuinely do very little. Here's how to actually fix the gut, in the order we'd talk you through it in store.

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Product Price Best for Buy
Florish Spore Probiotic with Fulvic Acid - 60 Capsules | One Life Health Florish Spore Probiotic with Fulvic Acid - 60 Capsules Best overall R 440.06 Best overall gut support
RAWBIOTICS - GUT CORRECT PROBIOTIC - 1L | One Life Health RAWBIOTICS - GUT CORRECT PROBIOTIC - 1L Liquid R 379.00 Best liquid daily support
WILLOW - Friendly Flora 12st - 20bil - 30 Capsules | One Life Health WILLOW - Friendly Flora 12st - 20bil - 30 Capsules Multi-strain R 334.00 Best multi-strain capsule
CREDENCE PHARMA - FulviAct FulviFlora Probiotic - 10 Capsules | One Life Health CREDENCE PHARMA - FulviAct FulviFlora Probiotic - 10 Capsules Budget R 86.25 Best low-cost trial
RAWBIOTICS - KIDS BALANCE PROBIOTIC - 1L | One Life Health RAWBIOTICS - KIDS BALANCE PROBIOTIC - 1L Kids R 347.00 Best for children

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Who this is for

If you bloat after meals; if your bowel habits have changed; if you've taken antibiotics in the last six months; if you've been told you have IBS; if your skin is unsettled and you suspect the gut is involved — this is for you. Crohn's, ulcerative colitis, coeliac disease, and red-flag symptoms (see end of article) need a GP, not a supplement aisle.

The short version

  • Fibre, not probiotics, is the foundation. Most South Africans eat 12–18 g/day. The target is 28–35 g. Fixing this alone solves 60% of gut problems.
  • Probiotics work best when matched to the problem: Saccharomyces boulardii for post-antibiotic; Bifidobacterium infantis 35624 for IBS-D; Lactobacillus plantarum 299v for IBS bloating.
  • Digestive enzymes help if you're over 50, on PPIs, or notice undigested food.
  • L-glutamine at 5 g supports the gut lining, particularly after antibiotics or alcohol-heavy stretches.
  • Apple cider vinegar helps low stomach acid (reflux often is, not the other way round).

Start with fibre, not pills

The gut microbiome is essentially a fibre-fermentation factory. Without fibre — particularly the soluble fibre in oats, legumes, vegetables, and seeds — even the best probiotics have nothing to eat. They pass through and exit. This is why most people see no benefit from probiotics: they've changed the staff but left the warehouse empty.

If your fibre intake is currently low, ramp up gradually. Going from 15 g to 35 g overnight will cause a week of bloating that will convince you fibre is the enemy. Add 5 g per week, drink more water, and you'll be at target inside a month.

Probiotics — the strain matters more than the brand

You can spend R200 or R600 on a probiotic, but if the strain isn't matched to your problem, both prices are wasted. Here are the strains with real clinical evidence for specific conditions:

  • Saccharomyces boulardii — antibiotic-associated diarrhoea, traveller's diarrhoea, post-antibiotic recovery. The one to take when your GP gives you a course of antibiotics.
  • Bifidobacterium longum 35624 (Bifantis) — IBS, particularly the diarrhoea-predominant variety.
  • Lactobacillus plantarum 299v — bloating, IBS flatulence, post-meal discomfort.
  • Lactobacillus rhamnosus GG — paediatric gastro, broad immune support.
  • Multi-strain blends with at least 20 billion CFU — for general restoration after antibiotics or a difficult period.

Browse our gut health collection and look at the strain names on the back, not the brand on the front. If you're not sure, ask in-store — we'll match the strain to your symptom.

Digestive enzymes — for the over-50s and the PPI crowd

Stomach acid drops with age and with long-term use of proton pump inhibitors (Nexiam, Pantoloc, Omezol). Low stomach acid causes a paradoxical reflux because food sits and ferments rather than moving through. If you're over 50, or have been on PPIs for years, or notice undigested food in stools, digestive enzymes (a broad-spectrum pancreatin + bromelain blend taken with meals) can quietly transform digestion within two weeks.

L-glutamine — the gut lining

The cells lining the small intestine turn over every 3–5 days and run on glutamine. After antibiotics, NSAIDs, or chronic stress, the lining can become more permeable ("leaky gut" in casual language, "increased intestinal permeability" in the clinical literature). 5 g of L-glutamine in water in the morning, for 4–6 weeks, gives the lining the raw material to rebuild. It's not a daily forever supplement — it's a recovery tool.

Apple cider vinegar and the reflux paradox

If you've been told you have acid reflux and put on a PPI, here's an uncomfortable truth: a meaningful portion of reflux is caused by low stomach acid, not high. The lower oesophageal sphincter closes when the stomach detects sufficient acid. If acid is too low, the sphincter doesn't close, and what acid there is leaks up. Treating with a PPI temporarily relieves symptoms but worsens the underlying problem.

Test (carefully, with your GP's input): 1 tsp of apple cider vinegar in water before a meal. If symptoms improve, you have a stomach-acid problem masquerading as reflux. If symptoms worsen, you have classic reflux and PPIs are correct.

What's overhyped

  • Generic probiotic blends sold without strain names — usually under-dosed and unmatched to your problem.
  • Bone broth as a gut cure — it's fine food, not a cure. The collagen survives boiling but the gut-healing claims outpace the evidence.
  • Charcoal pills — they bind nutrients and medications indiscriminately. Useful in acute food poisoning, not as a daily supplement.
  • Detox teas — laxatives in marketing dress. Skip.

Red flags — see a clinician now

The following are not gut-supplement problems: blood in stools, persistent diarrhoea longer than two weeks, unexplained weight loss, severe abdominal pain, vomiting that persists, fever with gut symptoms, family history of colon cancer with new symptoms over 45. Please book a GP appointment first. Our staff will say the same in person.

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Every product mentioned in this guide, curated by our pharmacists. STACK5 takes 5% off any stack.

Educational content only. Not medical advice. If symptoms are persistent, severe, or accompanied by red-flag signs, see your GP. Supplements can interact with medications — particularly blood thinners, immunosuppressants, and chemotherapy. Always disclose what you're taking to your clinician.

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